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226 Additionally, in breast cancer-associated fibroblasts, miR-205 mediates VEGF-independent angiogenesis through the YAP1-IL-11/IL-15-STAT3 axis, providing new strategies to combat resistance to anti-VEGF treatments

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c-Met is overexpressed in multiple human cancers including gastric, lung, colorectal, and hepatocellular carcinoma, where aberrant HGF/c-Met signaling drives tumor growth, invasion, and metastasis